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'Nicotine is a stimulant that affects the brain in much the same way as coffee the harm comes from how it is ingested.' Are Nicotine Pouches as Addictive as Cigarettes

Interestingly, an increased number of corticotropin releasing hormone neurons in the paraventricular nucleus has been observed in individuals diagnosed with major depressive disorder, as compared to healthy controls (130), suggesting clinical relevance of the findings from mice

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