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For current smokers, the evidence is mixed: several cross-sectional studies have reported a significant positive association with HTN 7,8 , while others, including some longitudinal investigations, have found no significant link or even an inverse relationship 6,7
It has long been known that smoking is harmful to the lungs and heart, though not as much research has been dedicated to its effect on the brain
As indicated above, this may be in a derived form in which one or more carboxylic functions is / are in the form -C (= O) -R 3 where R 3 may represent a radical -OY where Y represents an alkaline cation , a halogen, or a radical -OR 4 , -OC (= O) R 4 or -NR 4 R 4 ' , where R 4 and R 4 are independently C 1-12 alkyl radicals
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