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However, its still possible to be deficient, especially if you: have certain medical conditions, such as pernicious anemia and Crohns disease take certain medications, such as proton pump inhibitors follow a strict vegan or vegetarian diet The following symptoms may signal youre not getting enough B vitamins: fatigue weakness dyspnea (shortness of breath) heart palpitations loss of appetite headaches mouth ulcers swollen tongue irritability depression indigestion diarrhea cognitive changes, such as confusion and memory problems Speak with a healthcare professional if you experience any of these symptoms