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Discussion Understanding how nicotine affects decision-making has been challenging, because two different physiological aspects need to be distinguished 41 : (i) nicotine as a reinforcer that directly activates the dopaminergic system to produce reinforcement and nicotine-seeking, and (ii) nicotine as a neuromodulator that alters nicotine-independent decision-making processes by modifying the dynamics and computational properties of cholinoceptive circuits

The choice to pool multiple waves was made to improve statistical power for relatively uncommon exposure subgroups, particularly current exclusive e-cigarette users and current dual users, while maintaining a nationally representative adult sample

Without ventilation, the risks of both secondhand and thirdhand smoke are significant, potentially impacting others even after smoking has stopped

States consider menthol cigarette bans as feds delay action Elijah Kinlaw, 24, smokes after his shift at a local roofing company in Central Florida