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These potential intervention types were then reviewed by the research team against the APEASE criteria (Affordability, Practicability, Effectiveness and cost effectiveness, Acceptability, Side effects/safety and Equity), considering relevance and feasibility within the context of the NSW public antenatal care system, with reduction in the number retained

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In contrast to the other studies, which aimed to inhale CO in a fixed dose (e.g., 250 ppm), the investigators used the COVOX device, a small tool giving a specific dose of CO dependent on the bodyweight and the breathing cycle to the participant