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The upstream and downstream regulators of NLRP3 in APAP-induced liver injury are summarized in Tables 1 and 2

214,215,216,217 Additionally, sensory neurons in the dorsal root ganglia (DRG) exhibit altered phenotypes, such as reduced neurofilament synthesis, endoplasmic reticulum stress, and changes in key plasticity molecules, such as growth-associated protein 43 (GAP43) and heat shock proteins, leading to mitochondrial dysfunction and loss of peripheral nerve function

(Source: Asia Pacific is expected to grow at the fastest rate in the market during the forecast period due to the increasing disposable incomes, rising health awareness, and growing availability of global supplement brands