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SIgA serves as an immune exclusion antibody, binding to pathogens and toxins in the lumen to prevent them from adhering to the epithelium or penetrating the gut barrier (237)

It covers why semaglutide and tirzepatide work on different timelines, why appetite suppression arrives before weight loss does, why your neighbor lost ten pounds in month one while you lost three, and what the clinical trial data actually says about realistic expectations

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