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HDAC6 inhibitors such as tubastatin A and the clinically approved ACY-1215 (rocilinostat) enhance aggresome formation and autophagic clearance, reducing tau and -synuclein aggregates in AD and PD models

The empiric use of naloxone in patients with altered mental status: a reappraisal

Acetaminophen readily crosses the blood-brain barrier, and the central nervous system (CNS) is considered to be the primary site of action of the drug [1]