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Needle re-use and lipohypertrophy Studies show that the frequency at which needles are changed affects the risks of lipohypertrophy, with greater needle re-use linked to higher incidences of lipohypertrophy Needle tip breakages Studies show that excessive re-use of needles (use of a needle more than 7 times) caused very small pieces from the end of the needle to break off, suggesting that microscopic pieces of the needle may be left in the patient

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