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These DAMPs activate the innate immune system, particularly Kupffer cells (liver-resident macrophages) and recruited monocytes, which release proinflammatory cytokines like TNF-, IL-1, and IL-6

The name comes from the Marvel character Wolverine, whose defining trait is near-instant regenerative healing

Furthermore, five boys (815 years old) with attention deficit hyperactivity disorder (ADHD) were treated with L-theanine and caffeine, and the result showed that L-theanine combined with caffeine could effectively treat ADHD-related injuries in sustained attention, inhibitory control, and overall cognitive performance (64)

npj Biofilms Microbiomes 12 , 122 (2026)