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What I found when looking at the data across all three drugs is that the difference between tirzepatide and retatrutide, while real, is not massive for most people

Dual SGLT-2 inhibitor/GLP-1 receptor agonist treatment is not currently funded, unless the patient is receiving empagliflozin alone, or in combination with metformin for the treatment of heart failure

Although consensus was not consistently achieved regarding the prioritisation of BMI when choosing between SGLT2is and GLP-1 RAs, BMI was still recognised as one of the clinical factors that influences decision-making

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