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Normal aging in rodents, nonhuman primates and humans seems to particularly affect the hippocampus and the dorsal prefrontal cortex, brain areas crucial for episodic memory and working memory, respectively

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In comparison to the control group accepting only carbohydrates, the test group showed: - a larger share of adipose tissue in the process of generating energy during physical effort at an intensity of 50% VO2 max, - better energy production at an intensity of 80% VO2 max, - better physical performance by 11% (Wall et al., 2011)

(PubMed) Hiltunen JK, Autio KJ, Schonauer MS, Kursu VA, Dieckmann CL, Kastaniotis AJ