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Funding This research was supported by the China Postdoctoral Science Foundation (2021M701420), Guangdong Basic and Applied Basic Research Foundation (2022A1515110021), Guangzhou Science and Technology Projects Foundation (202201020002), Scientific Research Project of Guangdong TCM Bureau (20221105), Guangdong Medical Research Foundation (A2022214)

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5 Conclusions The rich content of phycocyanin, carotenoids, and polyphenols in Spirulina effectively neutralizes ROS, upregulates endogenous antioxidant enzymes, and downregulates pro-inflammatory mediators such as IL-6 and TNF-

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