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They have lots of advice on using Vitamin B12

Some of the serious side effects of Vitamin B12 include serous allergic reaction, narrowing or blocking of blood vessels, thrombocytosis (a disorder where your body produces too many platelets), low potassium levels in body, pulmonary edema (a condition where there is excess fluid in the lungs) and congestive heart failure

However, practices without negotiated contracts receive significantly lower out-of-network reimbursement, often 40-60% of standard Medicare allowances

A common protocol, for example, is to begin with about 20 mg of NAD+ administered subcutaneously and gradually increase the dose over subsequent injections up to around 100 mg per injection