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Frontin-Rubio et al

These cycles include the oxidation and reduction of glutathione which enables glutathione to react with free radicals before they cause damage

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Activation of the NRF2 pathway, including induction of NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1), promotes autophagic clearance and restrains over-activation [87] (Fig