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Through histone modification, curcumin downregulates histone acetyltransferases (p300/CBP) and histone deacetylases (HDAC1, HDAC3), restoring normal chromatin architecture and transcriptional activity of growth-regulating genes (Reuter et al., 2011)

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The human body produces L-carnitine in small amounts, but levels can vary based on diet, genetics, and lifestyle factors