These drugs include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is actually a dual GIP/GLP-1 receptor agonist
Pro-inflammatory chemicals called cytokines (IL-6, TNF-) and prostaglandins contribute to fibroid growth and the heavy bleeding associated with them. Women with higher dietary inflammatory index scores show greater fibroid risk in observational data. Insulin and Insulin-Like Growth Factor Insulin resistance and hyperinsulinemia stimulate IGF-1, which acts on fibroid tissue growth receptors
These processes commonly result in increased bioavailability of ROS due to excess ROS formation, decreased nitric oxide (NO) levels, and impaired antioxidant capacity in the arteries, heart, brain, and kidneys (133, 134)
[7] Jennifer E