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Mitochondrial ROS are increased under hypoxia, ischemia/reperfusion injury, chemical stress, drug treatment, and under many pathophysiological conditions (Srinivasan and Avadhani, 2012)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 217.Dry N., Pilgrim M., Gibala M., Gillen J., Wojtowicz J.M., Macqueen G., Becker S

The condition affects the autonomic nervous system's ability to regulate cardiovascular responses to postural changes, leading to a constellation of symptoms that can significantly impact quality of life