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They were connected to the side chain end of K10 P of peptide 20, allowing unambiguous assignment of the binding sites of lipidated K10 P with a 16-carbon palmitic acid through a -carboxylate spacer (Fig

For comparison, semaglutide alone achieved approximately 14.9% in the STEP 1 trial, and tirzepatide achieved approximately 20.9% in SURMOUNT-1 at 72 weeks

However, patients exhibited a trend towards lower capillary-to-fiber ratios ( p = 0.08, degrees of freedom 46), and capillary-to-fiber ratio correlated to VO 2max in both groups with identical slope and intercept (Fig

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