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Adverse Effects and Reporting Adverse events or suspected contamination issues should be reported immediately to the manufacturer (Hospira/Pfizer) and relevant regulatory authorities (FDA MedWatch, poison control, or institutional pharmacovigilance systems)

The US Food and Drug Administration (FDA) has approved 6 medications for long-term use, including orlistat, phentermine plus topiramate, naltrexone plus bupropion, subcutaneous liraglutide, subcutaneous semaglutide, and subcutaneous tirzepatide

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Board-certified physicians review submitted information to identify absolute contraindications including personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, pregnancy or breastfeeding, and documented serious allergic reactions to GLP-1 medications