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Results Propionate stimulates the release of PYY and GLP-1 from primary murine L cells In primary murine colonic cultures, physiological concentrations of propionate (150 mmol l 1 ) 20 significantly stimulated GLP-1 and PYY secretion over a 2-h incubation (Figures 1a and c)

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The same idea is paralleled in the conversion of NAC to glutathione, where genetic variants can also play a role

Constipation is classified as a syndrome and may include the infrequent (fewer than three a week) or difficult passage of stool, hardness of stool, and/or a feeling of incomplete evacuation