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Neuroprotection Against Parkinsons Models MPTP selectively destroys nigrostriatal dopaminergic neurons, producing tremor, rigidity, akinesia, and catalepsy in rodents

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3, 21, 22, 23 Most notably, the Aston-Jones group has found that the LS is an important relay center between the hippocampus and the ventral tegmental area (VTA) for information about cocainecontext associations and that the LS is necessary for the formation of cocaine conditioned place preference (CPP)