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Thus, based on the understanding of the role of the HGF/c-Met signaling pathway and the uniqueness of c-Met in HCC, more and more therapeutic strategies target c-Met and the interaction between c-Met and downstream signaling mediators instead of the interaction between HGF and c-Met because of the varying activation of c-Met

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It is estimated that 130 million Americans currently live with a condition eligible to be treated with a GLP-1 agonist, and that up to 70 million Americans may use a GLP-1 by 2028