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The compound appears to work by increasing intracellular NAD+ levels (through preventing nicotinamide consumption by NNMT), which activates sirtuins and enhances mitochondrial function and fatty acid oxidation, while also promoting a phenomenon called "browning" of white adipose tissue - the transformation of energy-storing white fat cells into metabolically active beige/brown adipocytes that burn fatty acids for thermogenesis rather than storing them

Many people are eager to see results quickly and skip the lower doses, but the microdosing and titration data shows that gradual escalation produces better long-term outcomes

its a fat-soluble hormone

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