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Because of glutaredoxin's similarities to thioredoxin, the mutated protein may be immediately exapted into the thioredoxin-dependent redox cycle upon addition of the second cysteine

[] DFO is a specific chelating agent for iron-related illnesses such as transfusion-dependent haemoglobinopathies that results in humoral iron overload

A healthy skin barrier prevents excessive water loss, excludes harmful microorganisms and irritants, and maintains the optimal environment for normal cellular function

Biochim Biophys Acta 1837(1):5162 Zhou R, Pantel AR, Li S et al (2017) [(18)F](2S,4R)4-Fluoroglutamine PET detects glutamine pool size changes in triple-negative breast cancer in response to glutaminase inhibition