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However, four fusions with a single point mutation (G2V, E15A, V19A and L26I) had potency at human GLP-1R similar to the target value and were investigated further for in vivo peptide stability and manufacturability

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Porpora MG, Tomao F, Manganaro L, Yazdanian D, Fuggetta E, Piccioni MG, Benedetti Panici P, Benagiano G (2014) Impaired uterine artery flow associated with the presence of ovarian endometrioma: preliminary results of a prospective study