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Although obese mice are not identical to obese humans, the results are highly suggestive

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10.2174/1874192401004010302 44 SarduC.PaolissoP.SacraC.SantamariaM.De LuciaC.RuoccoA.et al (2018)

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The six-membered ring to which the -lactam is fused in cephalosporins, results in lower tension within the -lactam ring compared to those of penicillins, and therefore less reactivity against thiolate anions (Perez-Inestrosa et al., 2005)

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