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Glutathione for Vascular and Cellular Brightening: Glutathione reduces oxidative cellular stress around the eye area, shifting melanin synthesis toward the lighter Phaeomelanin pathway and providing antioxidant protection that addresses the oxidative component of both surface pigmentation and the vascular visibility that makes discolouration in this area more pronounced

Its not a clinical diagnosis, nor is it discussed with the same frequency as GI discomfort

Researchers are still working to fully understand the specifics, but several pathways appear to be at play

Inflammatory and metabolic dysregulation and the 2-year course of depressive disorders in antidepressant users