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In terms of safety, adverse reactions from Survodutide were similar to those associated with conventional GLP-1R agonists when compared to the placebo, including nausea (66% vs
14,15,16 Mendelian randomization studies have demonstrated no causal relationship between elevated uric acid levels and the risks of diabetes, coronary heart disease, ischemic stroke, heart failure, body mass index, bone mineral density, coronary artery disease, blood pressure, metabolic syndrome, blood glucose levels, triglyceride levels, diabetes mellitus, serum creatinine levels, glomerular filtration rate, and Parkinsons disease
132(8 Suppl): 2367S-2372S