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Furthermore, transcriptome analysis revealed no significant differences in the expression levels of genes related to GSH synthetic pathways between wild-type and hepsin / mice (Fig

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Platelet activation relieves liver portal hypertension via the lymphatic system though the classical vascular endothelial growth factor receptor 3 signaling pathway

Interestingly, as shown in our transcriptome data, in addition to the pronounced enrichment of genes associated with JA signaling in systemic leaf tissues after GSH treatment, genes responsive to other defense phytohormones such as ethylene and salicylic acid, which are responsible for plant resistance to pathogen infection, are also highly upregulated (Supplementary Data 1), implying that GSH might also act as a signaling molecule to activate the plant systemic immune response