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FOXO4-p53 Disruption Moderate Research Detailed mechanistic studies confirm that FOXO4-DRI achieves its senolytic effects through precise disruption of the protective FOXO4-p53 protein interaction that allows senescent cells to evade apoptosis and persist in tissues

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I didnt know which was worse, eagerly expecting him, but never knowing when he might barge drunkenly through the door late at night to fight with Mom, or fearing he would never come home again at all