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Nuclear factor erythroid 2-related factor 2 (Nrf2), a critical modulator of antioxidant signaling, regulates the transcription of various genes coding antioxidant enzymes and cytoprotective proteins [17]

To encourage more accurate results, patients were asked to review treatments only if they had a good idea of their effects, whether positive, negative, or neutral

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Nausea, vomiting, diarrhea, constipation, and abdominal pain were mainly transient and mild to moderate